|"Are you a wizard or not?"
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Muggle supremacy is an ideology regarding Muggles are superior beings while wizards and witches are some sort of abnormal or even mentally deficient freaks.
The Dursleys eventually led their son Dudley Dursley into disgust of magical people, although Dudley's reluctance may primarily based on fear, not hate (for example, Dudley's first encounter with a wizard resulted in his getting a pig tail). While Vernon and Petunia often showed their strong hate toward the whole wizarding world, Dudley obviously did not hate all wizards, as he never insulted or bullied someone purely because that one had magical abilities.
In colonial North America, the Scourers interbreed with muggles and told their non-magical descendents that magic is real and that witches and wizards are evil. By the 1920's the New Salem Philanthropic Society has been established to expose and exterminate wizardkind.