Harry Potter and the Chamber of Secrets could refer to:
- Harry Potter and the Chamber of Secrets, the second book in the Harry Potter book series
- A character index
- Harry Potter and the Chamber of Secrets (film), the second film in the Harry Potter film series
- Harry Potter and the Chamber of Secrets (soundtrack), the soundtrack used in the film
- Harry Potter and the Chamber of Secrets (video game), the second video game in the Harry Potter video games series
- Harry Potter and the Chamber of Secrets (video game soundtrack), the soundtrack used in the video games