22 April is the 112th day of the year (113th in leap years). There are 253 days remaining until the end of the year.
- 1992: The Gryffindor first-years have an Astronomy Class at midnight, on the top of the Astronomy Tower.
- 1997: Harry Potter tells Ronald Weasley and Hermione Granger about Horace Slughorn's memory at Charms Class. Later, Katie Bell returns from St Mungo's Hospital for Magical Maladies and Injuries, but doesn't remember anything about who attacked her.